Funding Opportunity: NIH Director’s Early Independence Awards (DP5 Clinical Trial Optional)

If you have any questions about the internal coordination procedure for this program, please contact limitedprograms@research.ufl.edu.

The NIH Director’s Early Independence Award supports exceptional junior investigators who wish to pursue independent research soon after completion of their terminal doctoral degree or post-graduate clinical training, thereby forgoing the traditional post-doctoral training period and accelerating their entry into an independent research career. For the program to support the best possible researchers and research, applications are sought which reflect the full diversity of the research workforce. Individuals from diverse backgrounds, including those from underrepresented groups and from the full spectrum of eligible institutions in all geographic locations, are strongly encouraged to apply to this Funding Opportunity Announcement. In addition, applications in all topics relevant to the broad mission of NIH are welcome, including, but not limited to, topics in the behavioral, social, biomedical, applied, and formal sciences and topics that may involve basic, translational, or clinical research. The primary requirements are that the research be highly innovative and have the potential for unusually broad impact. The NIH Director’s Early Independence Award is a component of the High-Risk, High-Reward Research program of the NIH Common Fund.

To be eligible, investigators, at the time of application, must have received their most recent doctoral degree or completed clinical training within the previous fifteen months or expect to do so within the following twelve months. To be consistent with the updated NIH definition of Early Stage Investigators, eligible clinical training includes clinical residency and clinical fellowship.

Time window for eligibility: Given the focus on early research independence, the receipt date of the terminal doctoral degree or end of post-graduate clinical training of the PD/PI must be between June 1, 2020 and September 30, 2022. The degree receipt date is that which appears on the official transcript for the degree. The end of post-graduate clinical training includes residency and fellowship periods. The PD/PI must not have served as a post-doctoral fellow for more than twelve months before June 1, 2020.

At the time of award, either 1) the Early Independence investigator must have received a PhD, MD, DO, DC, DDS, DVM, OD, DPM, ScD, EngD, DrPH, DNSc, ND (Doctor of Naturopathy), PharmD, DSW, PsyD, or equivalent doctoral degree from an accredited domestic or foreign institution (it is the responsibility of the sponsoring institution to determine if a foreign doctoral degree is equivalent), or 2) an authorized official of the degree-granting or training institution must certify that all degree requirements have been met and that the receipt date of the degree (as will appear on the transcript) will be before September 30, 2023. An authorized official of the host institution must certify that the PD/PI will be able to conduct independent research at the institution at the time of the project start date.

Level of effort: Individuals must commit at least 9.6 person-months each year (i.e., 80% effort of a 12-month appointment) to the Early Independence Award project in years 1-2 of the project period. In years 3-5, awardees may reduce effort towards the Early Independence Award project but must commit at least 9.6 person-months each year (i.e., 80% effort of a 12-month appointment) to independent research in general.

Research independence at time of application: Individuals are eligible only if they, at the time of application submission, do not have research independence. Lack of research independence is defined functionally rather than by position title. Eligible individuals must have all the following characteristics:

  • The PD/PI’s current research agenda is set through concurrence with mentors.
  • The PD/PI’s research is funded primarily through support to other investigators (mentored fellowships such as NIH F31 or F32 Fellowships or NSF Graduate Research Fellowships do not preclude eligibility).
  • The PD/PI does not have any space assigned directly by the institution for the conduct of his/her research.
  • The PD/PI, according to institutional policy, cannot apply for an NIH R01 grant without special waiver or exemption from the institution.

Prospective applicants are encouraged to carefully review all eligibility requirements in the RFA at https://grants.nih.gov/grants/guide/rfa-files/RFA-RM-22-021.html

UF may only submit two (2) applications to this program.

TO SUBMIT: You will need to login to the UF|Research InfoReady site using your Gatorlink account to submit a concept for internal consideration for this opportunity. Clicking on the Apply button next to the opportunity details will display information to be uploaded.

Please note that if they receive more concepts than the allowed number by the sponsor, these concepts will be subject to review by ad-hoc reviewers.

If you have any questions about the internal coordination procedure for this program, please contact limitedprograms@research.ufl.edu.